Series in
MICROSYSTEMS
edited by P. A. Besse,
J. Brugger,
M. Gijs,
R. S. Popovic,
Ph. Renaud
Vol. 24:
Ulrike Lehmann
Manipulation
of Magnetic Microparticles
in Liquid Phases for On-Chip
Biomedical Analysis Methods.
2008. X, 162 p.; € 64,00.
ISBN-10: 3-86628-209-5
ISBN-13: 978-3-86628-209-4
Magnetic actuation
offers many advantages: long range of the force, insensitivity to environmental
influences and high force densities. In the last years these advantages led to
increased interest in using this type of actuation for Micro-Electro Mechanical
Systems (MEMS). In microfluidics and BioMEMS however, magnetic actuation plays only
a negligible role, while capillary or electroosmotic forces dominate.
This book
demonstrates that using magnetic microparticles inside channels or discrete
liquid volumes (microdroplets) augments the applicability of microfluidics
systems especially with respect to miniaturized bioanalytical procedures. The
magnetic microparticles can be used as mobile substrates for the transport of
biomolecules while they simultaneously serve as force mediators, which makes
it, among others, possible to manipulate aqueous droplets and to introduce
macroscopic bioanalytical protocols into microfluidic systems.
Ulrike Lehmann was born in Rostock,
Germany, in 1978. She received her Diploma in Electrical Engineering (Dipl.-Ing.)
with a specialization on Microsystem- and Device-Engineering from the TU Chemnitz,
Germany, in 2003. She subsequently joined the Institute of Microelectronics and
Microsystems at the Ecole Polytechnique Fédérale de Lausanne (EPFL),
Switzerland, as a research and teaching assistant. In 2008 she obtained her PhD
for her work on Lab-on-a-Chip systems based on the manipulation of magnetic
microparticles.
Keywords: Lab-on-a-Chip, Magnetic Microparticles, Microfluidics, Droplet
Manipulation, Bioanalysis, Optical Detection, Single Photon Avalanche Diode (SPAD).
Direkt bestellen bei / to order directly from: Hartung.Gorre@t-online.de