Selected
Readings in Vision and Graphics
edited by Luc Van Gool, Gábor
Székely, Markus Gross, Bernt Schiele
Volume 63
Robert H. P. McGregor
Enhancing Medical Images with High
Quality Blood Flow Information
2010. XVI,
172 pages. EUR 64,00. ISBN-10:
3-86628-343-1
ISBN-13: 978-3-86628-343-5
Cardiovascular diseases are the leading cause of
mortality in developed countries. Their pathogenesis and development are
complex and multifactorial, depending on a variety of biochemical and
biomechanical factors and are still not completely understood. Local
haemodynamics are increasingly recognised as a key component to the disease initiation process and yet there is a
lack of efficient tools for imaging such processes in-vivo, leading to a gap in
diagnostic capabilities and limited research possibilities. The objective of
this thesis is to investigate the enhancement of medical images with
high-quality blood flow information and to propose a novel, clinically
applicable approach. In an initial step, several methodological improvements to
the current computational blood flow simulation pipeline are presented focusing
principally on surface mesh generation, computational flow simulation using FEM
and FVM and fluid-structure interaction. Research is further concentrated on
creating an original flow measurement enhancement method, using a database of
precomputed simulations and principal component analysis to interpolate a
patient-specific flow field based on data acquired using medical imaging. The
experiments show this new approach to be highly promising and demonstrate it to
be a fast, clinically-feasible alternative to fully-blown flow simulation.
Author:
Robert McGregor obtained his M.Sc. (Dipl.-Ing.) degree in Mechanical Engineering from
the ETH Zurich in 2004. He performed his master thesis in collaboration with
Zimmer Orthopedics in the field of experimental orthopedic imaging and then
continued working for them in the same field. From 2006 until 2010 he worked as
a research assistant and PhD student in the field of medical imaging at the
Computer Vision Laboratory. In 2010 he was awarded a PhD degree (Dr. Sc. ETH)
from the ETH Zurich for his doctoral thesis “Enhancing Medical Images with High
Quality Blood Flow Information”.
Keywords: Computational Fluid Dynamics, Magnetic Resonance Imaging, Blood Flow
Measurement, Blood Flow Simulation, Mesh Generation, Flow Measurement
Enhancement, Biomedical Flow Imaging
Reihe
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